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This is a key concept and should be considered when patients are being evaluated for hormone therapy initiation. Spironolactone, which is relatively safe and inexpensive, is the most frequently used antiandrogen in the United States. Any concerning mood changes should be discussed with your primary care provider. Usually starts in months Reaches maximum effect in years Fewer morning erections Fewer spontaneous erections Not a permanent change if you stop taking hormones. Caitlyn Jenner's very public transition from man to woman has raised awareness about the concept of hormone therapy for transgender individuals. Milk discharge from the nipples can be a sign of elevated prolactin levels. WPATH recommends that hormone therapy should be initiated once psychosocial assessment has been completed, the patient has been determined to be an appropriate candidate for therapy, and informed consent reviewing the risks and benefits of starting therapy has been obtained. Published by Elsevier Inc.
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